mechanically it's rather simple since I'll roll a d20 for determining how things go, though if your character has something in his background or skills that would give them knowledge of how to do something than I'll either just outright let you do it or heavily weigh the roll in your favor. This will apply to whatever need to be rolled for including things like negotiations and making items, as well as combat.
Generally for dice rolls I use
https://www.wizards.com/d20modern/d20mdice/dice.htm since it lets me determine how many dice I'm rolling.