So The Reaper's Due came out for CK2 which greatly expands the "shit that can kill you" part of the game.
So I decided to start my first ironman run of the game for my ruler to die of rabies in the first year, then I played as a very healthy 70 year something man that lived until he was the ripe old age of 84. Now I'm playing as the shitty son that no one likes, has a wife who is dying from the shits, and three awful children that are becoming the worst kids I've ever had to raise.
I hope that this character dies soon so I can play as the one child that I managed to make into a paragon of virtue.