I'm generally against pre-ordering unless there's enough information about a game to know you'll enjoy it and pre-orders are what's funding the further development of the game.
So basically I'm against pre-ordering Fallout 4. However the only thing that's stopped me from pre-ordering it is that I'm unsure if my computer will be able to run it until I upgrade it, whenever that will be. The only reason I'd be okay with pre-ordering Fallout 4 is because I know I'm going to enjoy it.
But yeah, mindlessly pre-ordering things is ****ing stupid because it's 100% of the time more expensive than waiting like a month or two until after the game has come out and often times you don't really get anything worth the extra money.
Also I will find it the most hilarious thing if it turns out Fallout 4 has gone back to it's turn based roots, almost completely abandoning the new gameplay mechanics developed for Fallout 3 & NV. The incredible amount of people who have likely never actually seen Fallout 1&2 much less know what they're like, who will then proceed to lose their shit will be the best thing that has ever happened.